Creatine Monohydrate

Our pharmaceutical-grade creatine monohydrate is produced by a global leader in creatine research and manufacturing. This is the same form of creatine used in the majority of clinical studies, including the postmenopausal women trials cited below. Each batch undergoes rigorous third-party testing for purity, potency, and safety to ensure you receive the research-backed benefits.*

Clinical Profile

Creatine Monohydrate targets:

• Skeletal muscle performance

• Exercise capacity and endurance

• Muscle protein synthesis

• Support for high-intensity training

Primary Active

Creatine Monohydrate
 A widely studied compound produced in the liver and kidneys and delivered to skeletal muscle. Supplementation provides physiologically relevant doses to support exercise performance and muscle metabolism.

Key Benefits

• Research-grade creatine monohydrate

• Provides clinically relevant dosing for performance

• Supports skeletal muscle function and exercise capacity

• Manufactured in a GMP-certified, FDA-registered facility

Full Ingredient List

Creatine Monohydrate

Research Summary

Research shows that creatine monohydrate is one of the most studied and safest supplements available, with particular relevance for women during and after menopause. Clinical trials suggest that creatine, especially when combined with resistance training, may help support lean muscle, promote markers of bone strength, and assist with aspects of cognitive performance. Studies lasting one to two years have reported positive effects on indicators of bone health, while shorter trials suggest creatine may help support muscle energy and function. Additional research indicates it may also help the brain’s natural energy processes during times of stress or sleep disruption—common experiences during midlife. Taken consistently at 3–5 grams per day, creatine has a strong safety record over decades of use, with minimal side effects in healthy individuals, making it a well-researched option for supporting strength, bone health, and mental clarity during menopause.*

Research at a Glance

Key Citations

Primary Research in Menopausal Women:

1. Effects of creatine and resistance training on bone health in postmenopausal women. Med Sci Sports Exerc. 2015;47(7):1398-407. PubMed: 25386713

2. A 2-yr randomized controlled trial on creatine supplementation during exercise for postmenopausal bone health. Med Sci Sports Exerc. 2023;55(10):1789-1797. PubMed: 37144634

Supporting Research in Women:

1. Creatine supplementation and bone health in older women: a 2-year, randomized, placebo-controlled trial. J Gerontol A Biol Sci Med Sci. 2020;75(5):931-938. PubMed: 31257405

2. Creatine supplementation in fibromyalgia: a randomized, double-blind, placebo-controlled trial. Arthritis Care Res. 2013;65(9):1449-59. PubMed: 23554283

Additional Research:

1. Effect of creatine supplementation and sleep deprivation, with mild exercise, on cognitive and psychomotor performance, mood state, and plasma concentrations of catecholamines and cortisol. Psychopharmacology. 2006;185(1):93-103. PubMed: 16416332

2. Single dose creatine improves cognitive performance and induces changes in cerebral high energy phosphates during sleep deprivation. Sci Rep. 2024;14(1):4095. PubMed: 38418482

Important Disclaimer

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Always consult with your healthcare provider before starting any new supplement regimen, especially if you have pre-existing health conditions or are taking medications.

The research cited represents studies conducted on individual ingredients and may not reflect the specific formulation of this product. Individual results may vary based on sleep hygiene, stress levels, health status, and other factors. The research cited represents potential benefits and does not guarantee specific outcomes for all users.